Power Infusing Concentrate


Winner of 200 beauty awards globally – 1 Ultimune sold every 6.8 seconds


ULTIMUNE with The Lifeblood™, Power of Science.
Double Defenses* to Recharge Radiance in Just 3 Days
For Healthy Vibrant Skin

Our #1* best-selling serum just got stronger - Regardless of ethnicity, skin type, gender, age or living environment, Shiseido's new ULTIMUNE with ImuGenerationRED Technology™ enhances the fundamental flow of inner defenses and beauty circulation to maintain Healthy Vibrant Skin for all people. 

Powered with anti-oxidant rich reishi mushroom and iris root extracts, to strengthen skin, restore firmness and defend against daily damage for skin that’s 28% stronger in just 1 week.** Skin looks even smoother, firmer, more hydrated and resilient.  

  • The new formula features an improved dewy texture that sinks quickly into skin, for a longer-lasting, silky smooth fresh feeling.
  • For all skin types. Use Ultimune as a pre-treatment to enhance the efficacy of your moisturizer or serum. See makeup apply more evenly and flawlessly over softer skin.
  • Immediately, 96% said it moisturized their skin***
  • In 4 weeks,
    • 98% said the product was effective overall
    • 97% said it maintained the skin’s supple condition
    • 90% said it improved their skin condition
    • 91% felt it enhances effects of other skincare products they’re using

How to use

  • Push the pump twice to dispense formula onto palm of hand and smooth evenly over the face.
  • Use every morning and evening after cleansing and before moisturizing.
  • When using with other serums, first apply SHISEIDO ULTIMUNE Power Infusing Concentrate.


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